Concepedia

Compound Degradation Profiling

Compound Degradation Profiling is a methodological framework in in vitro metabolic assays that characterizes the metabolic instability and breakdown pathways of a test compound under controlled physiological conditions to elucidate its biotransformation mechanisms and pharmacokinetic liabilities.

267

Publications

8.4K

Citations

1.1K

Authors

349

Institutions

Publications per year

2017–2026

74

Parents

Publications

267

Host-compound foraging by intestinal microbiota revealed by single-cell stable isotope probing

David Berry, Bärbel Stecher, Arno Schintlmeister et al. · Proceedings of the National Academy of Sciences · 2013 · 248 citations · Full text

, , +17

The characteristics of enriched nitrifier culture in the degradation of selected pharmaceutically active compounds

Ngọc Hân Trần, Taro Urase, Osamu Kusakabe · Journal of Hazardous Materials · 2009 · 226 citations

, , +11

Comparison of MEA degradation in pilot-scale with lab-scale experiments

Hélène Lepaumier, Eirik F. da Silva, Aslak Einbu et al. · Energy Procedia · 2011 · 194 citations · Full text

, , +16

Incomplete aerobic degradation of the antidiabetic drug Metformin and identification of the bacterial dead-end transformation product Guanylurea

Christoph Trautwein, Klaus Kümmerer · Chemosphere · 2011 · 158 citations

, , +11

Catechin Degradation with Concurrent Formation of Homo- and Heterocatechin Dimers during <i>in Vitro</i> Digestion

Andrew P. Neilson, Amber S. Hopf, Bruce R. Cooper et al. · Journal of Agricultural and Food Chemistry · 2007 · 156 citations

, , +13

1–5 of 267

Authors

1.1K

  1. SS
    Saranjit Singh

    National Institute of Pharmaceutical Education and Research, India

    16 publications · 791 citations

    13

    h-index

  2. RS
    R. Srinivas

    Indian Institute of Chemical Technology, India

    13 publications · 289 citations

    11

    h-index

  3. RM
    Roshan M. Borkar

    Indian Institute of Chemical Technology, India

    9 publications · 205 citations

    9

    h-index

  4. AS
    Archana Sahu

    National Institute of Pharmaceutical Education and Research, India

    5 publications · 92 citations

    5

    h-index

  5. BC
    B. China Raju

    Indian Institute of Chemical Technology, India

    5 publications · 139 citations

    5

    h-index

1–5 of 1.1K

Institutions

349

  1. Indian Institute of Chemical Technology

    Hyderabad, India

    15 h-index

    76 publications

    1.5K citations

  2. National Institute of Pharmaceutical Education and Research - Ahmedabad

    Ahmedabad, India

    14 h-index

    59 publications

    1.6K citations

  3. National Institute of Pharmaceutical Education and Research

    Mohali, India

    13 h-index

    41 publications

    2K citations

  4. National Institute of Pharmaceutical Education and Research

    Hyderabad, India

    9 h-index

    23 publications

    458 citations

  5. Cairo University

    Giza, Egypt

    9 h-index

    21 publications

    584 citations

  6. Jawaharlal Nehru Technological University, Hyderabad

    Hyderabad, India

    8 h-index

    13 publications

    257 citations

  7. National Organization for Drug Control and Research

    Cairo, Egypt

    4 h-index

    7 publications

    108 citations

  8. Panacea Biotec (India)

    New Delhi, India

    4 h-index

    4 publications

    243 citations

1–8 of 349

Venues

  1. Journal of Pharmaceutical and Biomedical Analysis

    55 publications · 1.8K citations

    24

    h-index

  2. Chromatographia

    13 publications · 240 citations

    11

    h-index

  3. Journal of Chromatography A

    10 publications · 306 citations

    10

    h-index

  4. Analytical and Bioanalytical Chemistry

    7 publications · 164 citations

    7

    h-index

  5. RSC Advances

    6 publications · 113 citations

    6

    h-index

1–5