Population pharmacokinetics of voriconazole and <i>CYP2C19</i> polymorphisms for optimizing dosing regimens in renal transplant recipients

Abstract

Using a combination of CYP2C19 genotype and postoperative time to determine the initial voriconazole dosing regimens followed by therapeutic drug monitoring could help to advance individualized treatment in renal transplantation patients with invasive fungal infections.