Astilbin ameliorates cisplatin-induced nephrotoxicity through reducing oxidative stress and inflammation

Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis

Gina M. DeNicola, Florian A. Karreth, Timothy J. Humpton et al. · Nature · 2011 · 2.2K citations · Full text

Life Sciences, Molecular Biology, Oncology +14

The IκB Kinase Complex (IKK) Contains Two Kinase Subunits, IKKα and IKKβ, Necessary for IκB Phosphorylation and NF-κB Activation

Ebrahim Zandi, David M. Rothwarf, Mireille Delhase et al. · Cell · 1997 · 1.8K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +9

Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in <i>nrf2</i> transcription factor-deficient mice

Minerva Ramos‐Gómez, Mi-Kyoung Kwak, Patrick M. Dolan et al. · Proceedings of the National Academy of Sciences · 2001 · 1.1K citations · Full text

Life Sciences, Molecular Biology, Oncology +17

Acetate Is a Bioenergetic Substrate for Human Glioblastoma and Brain Metastases

Tomoyuki Mashimo, Kumar Pichumani, Vamsidhara Vemireddy et al. · Cell · 2014 · 783 citations · Full text

Medicine, Neuroscience, Oncology +15

TNF-α mediates chemokine and cytokine expression and renal injury in cisplatin nephrotoxicity

Ganesan Ramesh, William Reeves · Journal of Clinical Investigation · 2002 · 753 citations · Full text

Medicine, Pharmacology, Toxicology +17