ATP/P2X7-NLRP3 axis of dendritic cells participates in the regulation of airway inflammation and hyper-responsiveness in asthma by mediating HMGB1 expression and secretion

Glyburide inhibits the Cryopyrin/Nalp3 inflammasome

Mohamed Lamkanfi, James L. Mueller, Alberto C. Vitari et al. · The Journal of Cell Biology · 2009 · 808 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +17

Novel role of PKR in inflammasome activation and HMGB1 release

Ben Lü, Takahisa Nakamura, Karen Inouye et al. · Nature · 2012 · 760 citations · Full text

Life Sciences, Immunology, Molecular Biology +16

Extracellular ATP triggers and maintains asthmatic airway inflammation by activating dendritic cells

Marco Idzko, Hamida Hammad, Menno van Nimwegen et al. · Nature Medicine · 2007 · 620 citations

Life Sciences, Cell Biology, Immunology +14

Cutting Edge: Alum Adjuvant Stimulates Inflammatory Dendritic Cells through Activation of the NALP3 Inflammasome

Mirjam Kool, Virginie Pétrilli, Thibaut De Smedt et al. · The Journal of Immunology · 2008 · 607 citations · Full text

Life Sciences, Immunology, Adaptive Immunity +16

Inflammasome-Dependent Release of the Alarmin HMGB1 in Endotoxemia

Mohamed Lamkanfi, Anasuya Sarkar, Lieselotte Vande Walle et al. · The Journal of Immunology · 2010 · 458 citations · Full text

Life Sciences, Immunology, Pathobiology +17