Opioid Exposure is Associated with Aberrant DNA Methylation of OPRM1 Promoter Region in a Chinese Han Population

PROMO: detection of known transcription regulatory elements using species-tailored searches

Xavier Messeguer, Ruth Escudero, Domènec Farré et al. · Bioinformatics · 2002 · 1.4K citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +17

Identification of patterns in biological sequences at the ALGGEN server: PROMO and MALGEN

Domènec Farré · Nucleic Acids Research · 2003 · 1.1K citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +17

Identification of methylation haplotype blocks aids in deconvolution of heterogeneous tissue samples and tumor tissue-of-origin mapping from plasma DNA

Shicheng Guo, Dinh Diep, Nongluk Plongthongkum et al. · Nature Genetics · 2017 · 581 citations

Medicine, Genetics, Molecular Biology +11

DNA methylation and gene expression.

Aharon Razin, Howard Cedar · Microbiological Reviews · 1991 · 292 citations · Full text

Life Sciences, Genetics, Molecular Biology +16

Increased OPRM1 DNA Methylation in Lymphocytes of Methadone-Maintained Former Heroin Addicts

David A. Nielsen, Vadim Yuferov, Sara Hamon et al. · Neuropsychopharmacology · 2008 · 172 citations · Full text

Medicine, Molecular Biology, Pharmacology +14