Bioinformatics · 2002 · 1.4K citations · 6 references
Life SciencesBioinformaticsMolecular BiologyGenomicsSequence AnalysisTranscriptional RegulationCis-regulatory ElementsGene Regulatory ElementsMotif DiscoveryRegulatory GenomicsSequence Similarity SearchTranscription FactorsMotif ScanningPosition Weight Matrix EstimationRegulatory Dna Motif DiscoveryRegulatory Motif AnalysisRegulatory Motif DiscoveryTranscription Factor Binding Site AnnotationTranscription Factor Binding Site MappingTranscription Factor Binding Sites
Abstract Summary: We have developed a set of tools to construct positional weight matrices from known transcription factor binding sites in a species or taxon-specific manner, and to search for matches in DNA sequences. Availability: PROMO can be accessed online at http://www.lsi.upc.es/~alggen under the research link. Supplementary information: An example of the graphic interface (Figure 1) can be visualized at http://www.lsi.upc.es/~alggen/recerca/promo/figuraBioinformatics.html. Contact: peypoch@lsi.upc.es; m.alba@ucl.ac.uk * To whom correspondence should be addressed.
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The TRANSFAC system on gene expression regulation
Edgar Wingender · Nucleic Acids Research · 2001 · 663 citations · Full text