Concepedia

Stereochemistry and amyloid inhibition: Asymmetric triplex metallohelices enantioselectively bind to Aβ peptide

Yijia Guan, Nan Gao, Yue Cao, Xiaohui Wang, Peter Scott, H. L. Song, Jinsong Ren, Xiaogang Qu

Science Advances · 2018 · 81 citations · 53 references

DOIFull text

Open access

Concepts

Abstract

CL2006 strain by attenuating Aβ-induced toxicity. Our work will shed light on the design and screening of a metal complex as an amyloid inhibitor against Alzheimer's disease.

References

53

AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading

Oleg Trott, Arthur J. Olson · Journal of Computational Chemistry · 2009 · 37.1K citations · Full text

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Forecasting the global burden of Alzheimer's disease

Ron Brookmeyer, Elizabeth M. Johnson, Kathryn Ziegler‐Graham et al. · Alzheimer s & Dementia · 2007 · 3.4K citations

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Comparison of ABTS/DPPH assays to measure antioxidant capacity in popular antioxidant-rich US foods

Anna Floegel, Dae‐Ok Kim, Sang‐Jin Chung et al. · Journal of Food Composition and Analysis · 2011 · 1.8K citations

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EGCG remodels mature α-synuclein and amyloid-β fibrils and reduces cellular toxicity

Jan Bieschke, Jenny Russ, Ralf P. Friedrich et al. · Proceedings of the National Academy of Sciences · 2010 · 1K citations · Full text

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Structural characterization of toxic oligomers that are kinetically trapped during α-synuclein fibril formation

Serene W. Chen, Srdja Drakulić, Emma Deas et al. · Proceedings of the National Academy of Sciences · 2015 · 467 citations · Full text

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