Liver kinase B1/AMP‐activated protein kinase‐mediated regulation by gentiopicroside ameliorates P2X7 receptor‐dependent alcoholic hepatosteatosis - Concepedia

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Liver kinase B1/AMP‐activated protein kinase‐mediated regulation by gentiopicroside ameliorates P2X7 receptor‐dependent alcoholic hepatosteatosis

DOI Full Paper Access

93

Citations

41

References

2018

Year

Xia Li, Yu Zhang, Quan Jin, Kai‐Li Xia, Min Jiang, Ben‐Wen Cui, Yan‐Ling Wu, Shun‐Zong Song, Li‐Hua Lian, Ji‐Xing Nan

British Journal of Pharmacology

Abstract

Activation of LKB1/AMPK signalling by gentiopicroside was mediated by the P2X7 receptor-NLRP3 inflammasome, suggesting the therapeutic value of blocking P2X7 receptors in the treatment of alcoholic hepatosteatosis.

References

	Year	Citations

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