<scp>HLA</scp>‐<scp>DQA</scp>1‐<scp>HLA</scp>‐<scp>DRB</scp>1 polymorphism is a major predictor of azathioprine‐induced pancreatitis in patients with inflammatory bowel disease

Abstract

The class II HLA region (at rs2647087) is an important marker of AZA-induced pancreatitis risk. We propose a simple and clinically implementable algorithm based on rs2647087 and TPMT genotypes for AZA selection and dosing for patients with IBD.