Saikosaponin A inhibits compound 48/80-induced pseudo-allergy via the Mrgprx2 pathway in vitro and in vivo

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Life Sciences, Immunology, Pharmacology +14

A Diverse Family of GPCRs Expressed in Specific Subsets of Nociceptive Sensory Neurons

Xinzhong Dong, Sang-Kyou Han, Mark J. Zylka et al. · Cell · 2001 · 773 citations · Full text

Life Sciences, Neurobiology, Neuroscience +16

Immunoglobulin E-independent activation of mast cell is mediated by Mrg receptors

Kazuhiko Tatemoto, Yuko Nozaki, Ryoko Tsuda et al. · Biochemical and Biophysical Research Communications · 2006 · 419 citations

Life Sciences, Cell Biology, Immunology +11

In silico design of novel probes for the atypical opioid receptor MRGPRX2

Katherine Lansu, Joel Karpiak, Jing Liu et al. · Nature Chemical Biology · 2017 · 286 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +12

IL-33 promotes food anaphylaxis in epicutaneously sensitized mice by targeting mast cells

C Galand, Juan Manuel Leyva-Castillo, Juhan Yoon et al. · Journal of Allergy and Clinical Immunology · 2016 · 207 citations · Full text

Life Sciences, Immunology, Pathobiology +14