Quercetin inhibits Mrgprx2-induced pseudo-allergic reaction via PLCγ-IP3R related Ca2+ fluctuations

Yuanyuan Ding, Delu Che, Chaomei Li, +6

International Immunopharmacology

Molecular ImmunologyAllergyAllergy MedicineMedicineImmunology +8

Quercetin as a Lyn kinase inhibitor inhibits IgE-mediated allergic conjunctivitis

Yuanyuan Ding, Chaomei Li, Yongjing Zhang, +8

Food and Chemical Toxicology

AllergyAllergy MedicineMedicineImmunologyAllergen +7

MRGPRX2 is essential for sinomenine hydrochloride induced anaphylactoid reactions

Rui Liu, Delu Che, Tingting Zhao, +11

Biochemical Pharmacology

Medicinal ChemistryAnti-inflammatoryAllergyMedicineAnaphylactoid Reactions +3

Saikosaponin A inhibits compound 48/80-induced pseudo-allergy via the Mrgprx2 pathway in vitro and in vivo

Nan Wang, Delu Che, Tao Zhang, +7

Biochemical Pharmacology

InflammationAsthmaDrug HypersensitivityAutoimmune DiseaseAllergy +13

Typical antimicrobials induce mast cell degranulation and anaphylactoid reactions via MRGPRX2 and its murine homologue MRGPRB2

Tao Zhang, Delu Che, Rui Liu, +11

European Journal of Immunology

Mast cell-mediated hypersensitivity to fluoroquinolone is MRGPRX2 dependent

Rui Liu, Shiling Hu, Yongjing Zhang, +7

International Immunopharmacology

InflammationAllergyAutoimmune DiseaseMast Cell DisorderImmunology +5

Use of the relative release index for histamine in LAD2 cells to evaluate the potential anaphylactoid effects of drugs

Shengli Han, Yanni Lv, Liyun Kong, +10

Scientific Reports

Mivacurium induce mast cell activation and pseudo-allergic reactions via MAS-related G protein coupled receptor-X2

Delu Che, Jue Wang, Yuanyuan Ding, +7

Cellular Immunology

InflammationSignal TransductionAutoimmune DiseaseAllergyMast Cell Disorder +8

Cisatracurium induces mast cell activation and pseudo-allergic reactions via MRGPRX2

Delu Che, Rui Liu, Jiao Cao, +8

International Immunopharmacology

InflammationSignal TransductionAutoimmune DiseaseAllergyMast Cell Disorder +5

Mast Cells Initiate Type 2 Inflammation through Tryptase Released by MRGPRX2/MRGPRB2 Activation in Atopic Dermatitis

Tao Jia, Delu Che, Yi Zheng, +8

Journal of Investigative Dermatology

InflammationAtopic DermatitisMast Cell DisorderImmunologyInnate Immunity +6