3D‐Printing of Functional Biomedical Microdevices via Light‐ and Extrusion‐Based Approaches

Henry H. Hwang, Wei Zhu, Grace Victorine, Natalie Lawrence, Shaochen Chen

Small Methods · 2017 · 131 citations · 76 references

Concepts

TL;DR

3D‑printing is a powerful additive manufacturing tool that enables fabrication of biomedical devices and systems that would otherwise be difficult to create with traditional methods, with extrusion‑based and light‑based printers offering distinct advantages and limitations. The study showcases how extrusion‑based and light‑based 3D‑printing platforms can fabricate functional biomedical microdevices, evaluating their advantages, limitations, and current challenges while outlining future directions for improving printing techniques and device performance. The authors demonstrate fabrication of micromachines/robotics, drug‑delivery devices, biosensors, and microfluidics using these 3D‑printing platforms, addressing current challenges and proposing future improvements.

Abstract

Abstract 3D‐printing is a powerful additive manufacturing tool, one that enables fabrication of biomedical devices and systems that would otherwise be challenging to create with more traditional methods such as machining or molding. Many different classes of 3D‐printing technologies exist, most notably extrusion‐based and light‐based 3D‐printers, which are popular in consumer markets, with advantages and limitations for each modality. The focus here is primarily on showcasing the ability of these 3D‐printing platforms to create different types of functional biomedical microdevices—their advantages and limitations are covered with respect to other classes of 3D‐printing, as well as the past, recent, and future efforts to advance the functional microdevice domain. In particular, the fabrication of micromachines/robotics, drug‐delivery devices, biosensors, and microfluidics is addressed. The current challenges associated with 3D‐printing of functional microdevices are also addressed, as well as future directions to improve both the printing techniques and the performance of the printed products.

References

76