DDIAS suppresses TRAIL-mediated apoptosis by inhibiting DISC formation and destabilizing caspase-8 in cancer cells

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Life Sciences, Cell Biology, Molecular Biology +15

FLICE, A Novel FADD-Homologous ICE/CED-3–like Protease, Is Recruited to the CD95 (Fas/APO-1) Death-Inducing Signaling Complex

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Inhibition of death receptor signals by cellular FLIP

Martin Irmler, Margot Thome, Michael Hahne et al. · Nature · 1997 · 2.6K citations · Full text

Life Sciences, Cell Biology, Oncology +14

Tumoricidal activity of tumor necrosis factor–related apoptosis–inducing ligand in vivo

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Life Sciences, Oncology, Pharmacology +12

Involvement of MACH, a Novel MORT1/FADD-Interacting Protease, in Fas/APO-1- and TNF Receptor–Induced Cell Death

Mark Boldin, Tanya Goncharov, Yury V Goltseve et al. · Cell · 1996 · 2.3K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +12