Concepedia

Design, synthesis and biological evaluations of novel pyridone-thiazole hybrid molecules as antitumor agents

Wenlin Xie, Yiqiang Wu, Jingai Zhang, Qihong Mei, Yahan Zhang, Ning Zhu, Renzhi Liu, Huilin Zhang

European Journal of Medicinal Chemistry · 2017 · 125 citations · 13 references

DOI

Concepts

References

13

Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I.

Y H Hsiang, Robert Hertzberg, Sidney M. Hecht et al. · Journal of Biological Chemistry · 1985 · 2.4K citations · Full text

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New Synthetic Methods to 2-Pyridone Rings

Mercedes Torres, Salvador Gil, Margarita Parra · Current Organic Chemistry · 2005 · 220 citations

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Antimitotic and Antiproliferative Activities of Chalcones: Forward Structure–Activity Relationship

Ahcène Boumendjel, Julien Boccard, Pierre‐Alain Carrupt et al. · Journal of Medicinal Chemistry · 2008 · 174 citations

, , +13

Design, synthesis, antimicrobial evaluation and molecular docking studies of some new thiophene, pyrazole and pyridone derivatives bearing sulfisoxazole moiety

Tamer Nasr, Samir Bondock, Sameh Eid · European Journal of Medicinal Chemistry · 2014 · 132 citations

, , +13

Synthesis of some new 2-(3-pyridyl)-4,5-disubstituted thiazoles as potent antimicrobial agents

Samir Bondock, Tamer Naser, Yousry A. Ammar · European Journal of Medicinal Chemistry · 2013 · 127 citations

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