Exosomes derived from imatinib-resistant chronic myeloid leukemia cells mediate a horizontal transfer of drug-resistant trait by delivering miR-365

Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells

Hadi Valadi, Karin M. Ekström, Apostolos Bossios et al. · Nature Cell Biology · 2007 · 12.8K citations

Life Sciences, Genetics, Molecular Biology +12

Cancer Exosomes Perform Cell-Independent MicroRNA Biogenesis and Promote Tumorigenesis

Sónia A. Melo, Hikaru Sugimoto, Joyce T. O’Connell et al. · Cancer Cell · 2014 · 1.6K citations · Full text

Life Sciences, Cancer Biology, Molecular Biology +12

Exosomal transfer of stroma-derived miR21 confers paclitaxel resistance in ovarian cancer cells through targeting APAF1

Chi Lam Au Yeung, Ngai-Na Co, Tetsushi Tsuruga et al. · Nature Communications · 2016 · 789 citations · Full text

Medicine, Cancer Biology, Oncology +17

Exosomes derived from miR-122-modified adipose tissue-derived MSCs increase chemosensitivity of hepatocellular carcinoma

Guohua Lou, Xiuli Song, Fan Yang et al. · Journal of Hematology & Oncology · 2015 · 690 citations · Full text

Medicine, Cancer Biology, Oncology +17

Exosomes from Drug-Resistant Breast Cancer Cells Transmit Chemoresistance by a Horizontal Transfer of MicroRNAs

Wei‐xian Chen, Xuemin Liu, Mengmeng Lv et al. · PLoS ONE · 2014 · 418 citations · Full text

Medicine, Molecular Biology, Oncology +15