BMC Clinical Pathology · 2017 · 14 citations · 12 references
MedicineOncologyPathologyNeoplasiaSurgical PathologyTumor PathologyBenign Parotid TumorsBenign Salivary Gland TumorsBenign TumorsSalivary Gland CancerSalivary Gland MalignanciesSalivary Gland PathologyGross Pathologic ExaminationImmunohistochemical DetectionImmunohistochemical MarkersImmunohistochemical StainingParotid MassesSalivary Gland Tumor DiagnosisSpindle Cell Tumor HistopathologySpindle Cell Tumors
BACKGROUND: Solitary fibrous tumor is an uncommon spindle cell neoplasm of unknown origin. It has been reported in many anatomic sites, with a rare occurrence in the head and neck region. Solitary fibrous tumors of the parotid gland are exceptional; their clinical and radiologic features are non specific, often mimicking more common salivary gland tumors. Pathologic examination and immunohistochemistry are required to make the correct diagnosis. The prognosis is favorable, with most tumors being benign, and complete surgical resection is the treatment of choice. CASE PRESENTATION: We report the case of a 42-year-old man who presented with a painless mass involving the parotid gland. A parotidectomy was performed, and follow up was unremarkable. Gross examination showed a well circumscribed, firm tumor measuring 3,4 cm. Histologically, the tumor was composed of a spindle cell proliferation of variable cellularity, with staghorn vessels. A panel of immunohistochemical stains was performed, and confirmed the diagnosis of parotid gland solitary fibrous tumor. CONCLUSION: In this report we aim to increase awareness of this rare entity among clinicians and pathologists, and to emphasize the role of immunohistochemistry in confirming the diagnosis.
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Primary neoplasms of the pleura. A report of the five cases
Paul Klemperer · Medical Entomology and Zoology · 1931 · 921 citations
Clinicopathologic correlates of solitary fibrous tumors
Jason S. Gold, Cristina R. Antonescu, Cristina Hajdu et al. · Cancer · 2002 · 762 citations
NAB2–STAT6 fusion types account for clinicopathological variations in solitary fibrous tumors
Huichun Tai, I‐Chieh Chuang, Tse‐Ching Chen et al. · Modern Pathology · 2015 · 160 citations · Full text
Solitary Fibrous Tumors of the Head and Neck
Ian Ganly, Snehal G. Patel, Hilda E. Stambuk et al. · Archives of Otolaryngology - Head and Neck Surgery · 2006 · 150 citations