Cancer-Associated Fibroblasts Neutralize the Anti-tumor Effect of CSF1 Receptor Blockade by Inducing PMN-MDSC Infiltration of Tumors

Robust enumeration of cell subsets from tissue expression profiles

Aaron M. Newman, Chih Long Liu, Michael R. Green et al. · Nature Methods · 2015 · 14.1K citations · Full text

Life Sciences, Cell Biology, Immunology +16

The prognostic landscape of genes and infiltrating immune cells across human cancers

Andrew J. Gentles, Aaron M. Newman, Chih Long Liu et al. · Nature Medicine · 2015 · 3.3K citations · Full text

Medicine, Cancer Biology, Oncology +16

CSF-1R inhibition alters macrophage polarization and blocks glioma progression

Stephanie M. Pyonteck, Leila Akkari, Alberto J. Schuhmacher et al. · Nature Medicine · 2013 · 2.5K citations · Full text

Life Sciences, Neuroscience, Oncology +12

Targeting CXCL12 from FAP-expressing carcinoma-associated fibroblasts synergizes with anti–PD-L1 immunotherapy in pancreatic cancer

Christine Feig, James O. Jones, Matthew Kraman et al. · Proceedings of the National Academy of Sciences · 2013 · 2K citations

Medicine, Immunology, Oncology +17

Leukocyte Complexity Predicts Breast Cancer Survival and Functionally Regulates Response to Chemotherapy

David G. DeNardo, Donal J. Brennan, Elton Rexhepaj et al. · Cancer Discovery · 2011 · 1.7K citations

Medicine, Immunology, Oncology +17