A lysosomal switch triggers proteostasis renewal in the immortal C. elegans germ lineage

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Ravi S. Kamath, Andrew Fraser, Dong Yan et al. · Nature · 2003 · 3.7K citations

Life Sciences, Genetics, Molecular Genetics +12

Efficient gene transfer in C.elegans: extrachromosomal maintenance and integration of transforming sequences.

C C Mello, James M. Kramer, Dan T. Stinchcomb et al. · The EMBO Journal · 1991 · 3.2K citations · Full text

Life Sciences, Genetics, Molecular Genetics +8

Rejuvenation of aged progenitor cells by exposure to a young systemic environment

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Education, Cell Biology, Developmental Biology +14

RESPIRATORY ENZYMES IN OXIDATIVE PHOSPHORYLATION

Britton Chance, G. R. Williams · Journal of Biological Chemistry · 1955 · 1.5K citations · Full text

Life Sciences, Biochemistry, Physiology +12

Bafilomycin A1, a specific inhibitor of vacuolar-type H(+)-ATPase, inhibits acidification and protein degradation in lysosomes of cultured cells.

Tamotsu Yoshimori, Akira Yamamoto, Yoshinori Moriyama et al. · Journal of Biological Chemistry · 1991 · 1.4K citations · Full text

Life Sciences, Biochemistry, Cell Biology +14