NRF1 Is an ER Membrane Sensor that Is Central to Cholesterol Homeostasis

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

Da Wei Huang, Brad T. Sherman, Richard A. Lempicki · Nature Protocols · 2008 · 37.4K citations

Life Sciences, Bioinformatics, Molecular Biology +5

Switch-like Control of SREBP-2 Transport Triggered by Small Changes in ER Cholesterol: A Delicate Balance

Arun Radhakrishnan, Joseph L. Goldstein, Jeffrey G. McDonald et al. · Cell Metabolism · 2008 · 559 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

Hepatocyte-Specific Disruption of CD36 Attenuates Fatty Liver and Improves Insulin Sensitivity in HFD-Fed Mice

Camella G. Wilson, Jennifer L. Tran, Derek M. Erion et al. · Endocrinology · 2015 · 466 citations · Full text

Life Sciences, Biochemistry, Endocrinology +16

Direct Binding of Cholesterol to the Purified Membrane Region of SCAP

Arun Radhakrishnan, Li-Ping Sun, Hyock Joo Kwon et al. · Molecular Cell · 2004 · 334 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +12

Enrichment of Endoplasmic Reticulum with Cholesterol Inhibits Sarcoplasmic-Endoplasmic Reticulum Calcium ATPase-2b Activity in Parallel with Increased Order of Membrane Lipids

Yankun Li, Mingtao Ge, Laura Ciani et al. · Journal of Biological Chemistry · 2004 · 278 citations · Full text

Life Sciences, Biochemistry, Cell Biology +17