Concepedia

Cholesterol Sensing

Cholesterol Sensing is a molecular regulatory mechanism within nutrient-sensing pathways that detects intracellular cholesterol levels through specialized proteins or domains, thereby modulating downstream signaling cascades to maintain lipid homeostasis.

374

Publications

26.5K

Citations

2K

Authors

654

Institutions

Publications per year

2017–2026

147

Parents

Publications

374

Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRα and LXRβ

Joyce J. Repa, Guosheng Liang, Jiafu Ou et al. · Genes & Development · 2000 · 1.7K citations · Full text

, , +16

Murine Model of Niemann-Pick C Disease: Mutation in a Cholesterol Homeostasis Gene

Stacie K. Loftus, Jill A. Morris, Eugene D. Carstea et al. · Science · 1997 · 807 citations

, , +17

Antidepressant drugs act by directly binding to TRKB neurotrophin receptors

Plínio Casarotto, Mykhailo Girych, Senem Merve Fred et al. · Cell · 2021 · 665 citations · Full text

, , +17

Dispatched, a Novel Sterol-Sensing Domain Protein Dedicated to the Release of Cholesterol-Modified Hedgehog from Signaling Cells

Richard Burke, Denise Nellen, Manolo Bellotto et al. · Cell · 1999 · 576 citations · Full text

, , +14

An ARC/Mediator subunit required for SREBP control of cholesterol and lipid homeostasis

Fajun Yang, Bryan W. Vought, John S. Satterlee et al. · Nature · 2006 · 418 citations

, , +16

1–5 of 374

Authors

2K

  1. BD
    Bansi D. Malhotra

    CSIR National Physical Laboratory of India, India

    9 publications · 699 citations

    9

    h-index

  2. AR
    Arun Radhakrishnan

    The University of Texas Southwestern Medical Center, United States

    7 publications · 514 citations

    7

    h-index

  3. JL
    Joseph L. Goldstein

    The University of Texas Southwestern Medical Center, United States

    5 publications · 549 citations

    5

    h-index

  4. VG
    Vinay Gupta

    University of Delhi, India

    5 publications · 197 citations

    5

    h-index

  5. MS
    Michael S. Brown

    The University of Texas Southwestern Medical Center, United States

    5 publications · 549 citations

    5

    h-index

1–5 of 2K

Institutions

654

  1. The University of Texas Southwestern Medical Center

    Dallas, United States

    17 h-index

    78 publications

    13.6K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    9 h-index

    37 publications

    1.3K citations

  3. Inserm

    Paris, France

    8 h-index

    52 publications

    2.9K citations

  4. Chinese Academy of Sciences

    Beijing, China

    7 h-index

    30 publications

    2.5K citations

  5. Washington University in St. Louis

    St Louis, United States

    7 h-index

    18 publications

    2.1K citations

  6. Stanford University

    Stanford, United States

    7 h-index

    33 publications

    5.1K citations

  7. Howard Hughes Medical Institute

    Chevy Chase, United States

    7 h-index

    34 publications

    21.4K citations

  8. UNSW Sydney

    Sydney, Australia

    7 h-index

    17 publications

    941 citations

1–8 of 654

Venues

  1. Sensors and Actuators B Chemical

    20 publications · 1.1K citations

    18

    h-index

  2. Journal of Biological Chemistry

    JBC · 20 publications · 1.3K citations

    18

    h-index

  3. Biosensors and Bioelectronics

    18 publications · 1.9K citations

    18

    h-index

  4. Analytica Chimica Acta

    14 publications · 983 citations

    14

    h-index

  5. Talanta

    11 publications · 573 citations

    11

    h-index

1–5