Concepedia

RIP1K Contributes to Neuronal and Astrocytic Cell Death in Ischemic Stroke via Activating Autophagic-lysosomal Pathway

Yong Ni, Wei-Wei Gu, Zhi-He Liu, Yong-Ming Zhu, Jia-Guo Rong, Thomas A. Kent, Min Li, Shi-Gang Qiao, Jian-Zhong An, Hui-Ling Zhang

Neuroscience · 2017 · 80 citations · 24 references

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Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury

Alexei Degterev, Zhihong Huang, Michael Boyce et al. · Nature Chemical Biology · 2005 · 3K citations

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Receptor Interacting Protein Kinase-3 Determines Cellular Necrotic Response to TNF-α

Sudan He, Lai Wang, Lin Miao et al. · Cell · 2009 · 2.2K citations

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Identification of RIP1 kinase as a specific cellular target of necrostatins

Alexei Degterev, Junichi Hitomi, Megan Germscheid et al. · Nature Chemical Biology · 2008 · 2K citations · Full text

, , +14

Fas triggers an alternative, caspase-8–independent cell death pathway using the kinase RIP as effector molecule

Nils Holler, Rossana Zaru, Olivier Micheau et al. · Nature Immunology · 2000 · 1.9K citations

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3-Methyladenine: Specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes

Per O. Seglen, Paul B. Gordon · Proceedings of the National Academy of Sciences · 1982 · 1.3K citations · Full text

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