PTEN-L promotes type I interferon responses and antiviral immunity

<i>PTEN</i> , a Putative Protein Tyrosine Phosphatase Gene Mutated in Human Brain, Breast, and Prostate Cancer

Jing Li, Clifford Yen, Danny Liaw et al. · Science · 1997 · 4.8K citations

Medicine, Molecular Genetics, Oncology +16

The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses

Mitsutoshi Yoneyama, Mika Kikuchi, Takashi Natsukawa et al. · Nature Immunology · 2004 · 3.9K citations

Life Sciences, Immunology, Molecular Biology +16

Role of Adaptor TRIF in the MyD88-Independent Toll-Like Receptor Signaling Pathway

Masahiro Yamamoto, Shintaro Sato, Hiroaki Hemmi et al. · Science · 2003 · 3.2K citations

Life Sciences, Immunology, Molecular Biology +17

The Tumor Suppressor, PTEN/MMAC1, Dephosphorylates the Lipid Second Messenger, Phosphatidylinositol 3,4,5-Trisphosphate

Tomohiko Maehama, Jack E. Dixon · Journal of Biological Chemistry · 1998 · 3.1K citations · Full text

Life Sciences, Biochemistry, Cell Biology +17

Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

Peter A. Steck, Mark A. Pershouse, Samar A. Jasser et al. · Nature Genetics · 1997 · 2.8K citations

Life Sciences, Genetics, Molecular Genetics +11