Blood · 2017 · 121 citations · 48 references
Life SciencesGeneticsHematologyHematopathologyHuman GeneticsMedical GeneticsAneuploidyCongenital DisordersGenetic DisordersHematologic DisordersHematologic PathologyHematopoietic DevelopmentClonal Hematopoiesis FilteringCongenital PancytopeniaDevelopmental HematopoiesisHematologic AbnormalitiesHematopoietic DisordersInherited Bone Marrow Failure SyndromesSomatic Mutations
Key Points Hematopoietic stem/progenitor mutation burden is not increased in SCN. Clonal hematopoiesis due to mutations of TP53 is present in the majority of patients with SDS.
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Age-Related Clonal Hematopoiesis Associated with Adverse Outcomes
Siddhartha Jaiswal, Pierre Fontanillas, Jason Flannick et al. · New England Journal of Medicine · 2014 · 4.7K citations · Full text
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Age-related mutations associated with clonal hematopoietic expansion and malignancies
Mingchao Xie, Charles Lu, Jiayin Wang et al. · Nature Medicine · 2014 · 1.9K citations · Full text
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The Origin and Evolution of Mutations in Acute Myeloid Leukemia
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