Concepedia

Activation of Nrf2 might reduce oxidative stress in human granulosa cells

Nana Akino, Osamu Wada‐Hiraike, Hiromi Terao, Harunori Honjoh, Wataru Isono, Houju Fu, Mana Hirano, Yuichiro Miyamoto, Michihiro Tanikawa, Miyuki Harada,

Molecular and Cellular Endocrinology · 2017 · 63 citations · 25 references

DOI

Concepts

References

25

Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain

Ken Itoh, Nobunao Wakabayashi, Yasutake Katoh et al. · Genes & Development · 1999 · 3.6K citations · Full text

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Keap1-dependent Proteasomal Degradation of Transcription Factor Nrf2 Contributes to the Negative Regulation of Antioxidant Response Element-driven Gene Expression

Michael McMahon, Ken Itoh, Masayuki Yamamoto et al. · Journal of Biological Chemistry · 2003 · 1.1K citations · Full text

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Nrf2 enhances resistance of cancer cells to chemotherapeutic drugs, the dark side of Nrf2

X.-J. Wang, Zheng Sun, Nicole Villeneuve et al. · Carcinogenesis · 2008 · 842 citations · Full text

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Contribution of impaired Nrf2-Keap1 pathway to oxidative stress and inflammation in chronic renal failure

Hyun Ju Kim, Nosratola D. Vaziri · American Journal of Physiology-Renal Physiology · 2009 · 469 citations

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Reactive oxygen species are indispensable in ovulation

Ketty Shkolnik, Ari Tadmor, Shifra Ben‐Dor et al. · Proceedings of the National Academy of Sciences · 2011 · 394 citations · Full text

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