Publication | Open Access

Pathogenic mutation in the ALS/FTD gene, CCNF, causes elevated Lys48-linked ubiquitylation and defective autophagy

Pathogenic MutationCell AutophagyNeurodegenerative DiseasesAmyotrophic Lateral SclerosisMendelian DisorderDisease MechanismGeneticsAutophagyDefective AutophagyMolecular GeneticsAls/ftd GeneMedicineCell Biology