Protective effects of a G. lucidum proteoglycan on INS-1 cells against IAPP-induced apoptosis via attenuating endoplasmic reticulum stress and modulating CHOP/JNK pathways

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Endoplasmic reticulum stress contributes to beta cell apoptosis in type 2 diabetes

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Life Sciences, Cell Biology, Endocrinology +16

Unfolded Proteins Are Ire1-Activating Ligands That Directly Induce the Unfolded Protein Response

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Life Sciences, Biochemistry, Molecular Biology +14

Regulation of insulin biosynthesis in pancreatic beta cells by an endoplasmic reticulum-resident protein kinase IRE1

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Life Sciences, Endocrinology, Molecular Biology +16

High Expression Rates of Human Islet Amyloid Polypeptide Induce Endoplasmic Reticulum Stress–Mediated β-Cell Apoptosis, a Characteristic of Humans With Type 2 but Not Type 1 Diabetes

Chang-jiang Huang, Chia‐Yu Lin, Leena Haataja et al. · Diabetes · 2007 · 410 citations · Full text

Life Sciences, Cell Biology, Endocrinology +17