Sonya G. Fonseca

Regulation of insulin biosynthesis in pancreatic beta cells by an endoplasmic reticulum-resident protein kinase IRE1

Kathryn L. Lipson, Sonya G. Fonseca, Shinsuke Ishigaki et al. · Cell Metabolism · 2006 · 415 citations · Full text

Signal Transduction, Molecular Physiology, Biochemistry +10

Wolfram syndrome 1 gene negatively regulates ER stress signaling in rodent and human cells

Sonya G. Fonseca, Shinsuke Ishigaki, Christine M. Oslowski et al. · Journal of Clinical Investigation · 2010 · 394 citations · Full text

Genetics, Er Stress, Insulin Signaling +18

WFS1 Is a Novel Component of the Unfolded Protein Response and Maintains Homeostasis of the Endoplasmic Reticulum in Pancreatic β-Cells

Sonya G. Fonseca, Mariko Fukuma, Kathryn L. Lipson et al. · Journal of Biological Chemistry · 2005 · 362 citations · Full text

Molecular Biology, Cell Death, Er Stress +24

AATF mediates an antiapoptotic effect of the unfolded protein response through transcriptional regulation of AKT1

Shinsuke Ishigaki, Sonya G. Fonseca, Christine M. Oslowski et al. · Cell Death and Differentiation · 2009 · 66 citations · Full text

Inflammation, Reductive Stress, Transcriptional Regulation +12

Wolfram syndrome 1 and adenylyl cyclase 8 interact at the plasma membrane to regulate insulin production and secretion

Sonya G. Fonseca, Fumihiko Urano, Gordon C. Weir et al. · Nature Cell Biology · 2012 · 59 citations · Full text

Insulin Production, Adenylyl Cyclase 8, Molecular Physiology +12