Contrasting effects of phosphatidylinositol 4,5‐bisphosphate on cloned TMEM16A and TMEM16B channels

Abstract

PIP₂ acts as a modifier of TMEM16A and TMEM16B channel gating. Drugs interacting with PIP₂ signalling may affect TMEM16A and TMEM16B channel gating and have potential uses in basic science and implications for therapy.