PIP2 Activates KCNQ Channels, and Its Hydrolysis Underlies Receptor-Mediated Inhibition of M Currents

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

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Natural Sciences, Biophysics, Cell Biology +16

Positional cloning of a novel potassium channel gene: KVLQT1 mutations cause cardiac arrhythmias

Q. Wang, Mark Curran, Igor Splawski et al. · Nature Genetics · 1996 · 1.8K citations

Medicine, Genetics, Molecular Genetics +17

Muscarinic suppression of a novel voltage-sensitive K+ current in a vertebrate neurone

David A. Brown, Paul R. Adams · Nature · 1980 · 1.5K citations

Life Sciences, Neurobiology, Neuroscience +15

KCNQ2 and KCNQ3 Potassium Channel Subunits: Molecular Correlates of the M-Channel

H. Wang · 1998 · 1.3K citations

Life Sciences, Biophysics, Neuroscience +17

Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition

Huai-hu Chuang, Elizabeth D. Prescott, Haeyoung Kong et al. · Nature · 2001 · 1.3K citations

Medicine, Biochemistry, Pharmacology +8