Bioinformatics · 2017 · 16 citations · 9 references
ComputingBioinformaticsVisualizationInteractive VisualizationNetwork VisualizationScientific VisualizationMacromolecular AssemblyMolecular Interaction NetworksMolecular VisualizationMultivalent InteractionsProtein StructureProtein-ligand BindingBiomolecular Network VisualizationInteractive Molecular VisualizationMacromolecular Structure VisualizationMolecular Interaction Network VisualizationProtein Interaction Network VisualizationProtein Structure VisualizationScalable Vector Graphics
SUMMARY: Proteins frequently function as parts of complexes, assemblages of multiple proteins and other biomolecules, yet network visualizations usually only show proteins as parts of binary interactions. ComplexViewer visualizes interactions with more than two participants and thereby avoids the need to first expand these into multiple binary interactions. Furthermore, if binding regions between molecules are known then these can be displayed in the context of the larger complex. AVAILABILITY AND IMPLEMENTATION: freely available under Apache version 2 license; EMBL-EBI Complex Portal: http://www.ebi.ac.uk/complexportal; Source code: https://github.com/MICommunity/ComplexViewer; Package: https://www.npmjs.com/package/complexviewer; http://biojs.io/d/complexviewer. Language: JavaScript; Web technology: Scalable Vector Graphics; Libraries: D3.js. CONTACT: colin.combe@ed.ac.uk or juri.rappsilber@ed.ac.uk.
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