Antipsychotic medications and stroke in schizophrenia: A case-crossover study

Wen‐Yin Chen, Lian‐Yu Chen, Hsing-Cheng Liu, Chi‐Shin Wu, Shu-Yu Yang, Chun‐Hung Pan, Shang‐Ying Tsai, Chiao‐Chicy Chen, Chian-Jue Kuo

PLoS ONE · 2017 · 27 citations · 27 references

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Abstract

Use of second-generation antipsychotic drugs appeared to be associated with an increased risk of ischemic stroke in the patients studied, possibly mediated by high affinity for histamine-1 receptor blockade. Further research regarding the underlying biological mechanism and drug safety is suggested.

References

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