Lipopolysaccharide-induced murine embryonic resorption involves changes in endocannabinoid profiling and alters progesterone secretion and inflammatory response by a CB1-mediated fashion

Isolation and Structure of a Brain Constituent That Binds to the Cannabinoid Receptor

William A. Devane, Aviva Breuer, Roger G. Pertwee et al. · Science · 1992 · 5.6K citations

Life Sciences, Neuroscience, Pharmacology +15

Unresponsiveness to Cannabinoids and Reduced Addictive Effects of Opiates in CB ₁ Receptor Knockout Mice

Catherine Ledent, Olga Valverde, G Cossu et al. · Science · 1999 · 3.6K citations

Medicine, Neuroscience, Pharmacology +15

Nitric oxide mediates glutamate-linked enhancement of cGMP levels in the cerebellum.

David S. Bredt, S H Snyder · Proceedings of the National Academy of Sciences · 1989 · 1.8K citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Evidence That the Cannabinoid CB1 Receptor Is a 2-Arachidonoylglycerol Receptor

Takayuki Sugiura, Tomoko Kodaka, Shinji Nakane et al. · Journal of Biological Chemistry · 1999 · 313 citations · Full text

Medicine, Neuroscience, Pharmacology +14

Progesterone Receptor Plays a Major Antiinflammatory Role in Human Myometrial Cells by Antagonism of Nuclear Factor-κB Activation of Cyclooxygenase 2 Expression

Daniel B. Hardy, Bethany A. Janowski, David R. Corey et al. · Molecular Endocrinology · 2006 · 284 citations

Life Sciences, Cell Biology, Endocrinology +16