Thermo-Optical Protein Characterization for Straightforward Preformulation Development

Examination of Thermal Unfolding and Aggregation Profiles of a Series of Developable Therapeutic Monoclonal Antibodies

Mark L. Brader, Tia Estey, Shujun Bai et al. · Molecular Pharmaceutics · 2015 · 161 citations

Pharmacy, Biochemistry, Pharmaceutical Biotechnology +17

Thermal Trap for DNA Replication

Christof B. Mast, Dieter Braun · Physical Review Letters · 2010 · 148 citations

Life Sciences, Biophysics, Molecular Biology +15

Structural Characterization of IgG1 mAb Aggregates and Particles Generated Under Various Stress Conditions

Srivalli Telikepalli, Ozan S. Kumru, Cavan Kalonia et al. · Journal of Pharmaceutical Sciences · 2014 · 135 citations · Full text

Pharmacy, Biochemistry, Immunology +14

Novel microscale approaches for easy, rapid determination of protein stability in academic and commercial settings

Crispin G. Alexander, Randy Wanner, C. Mark Johnson et al. · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics · 2014 · 107 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

High‐Throughput Assessment of Thermal and Colloidal Stability Parameters for Monoclonal Antibody Formulations

Feng He, Christopher Woods, Gerald W. Becker et al. · Journal of Pharmaceutical Sciences · 2011 · 106 citations

Pharmacy, Molecular Pharmaceutics, Pharmaceutics +16