Generation and characterization of aptamers targeting factor XIa

Factor XI Antisense Oligonucleotide for Prevention of Venous Thrombosis

Harry R. Büller, Claudette Bethune, Sanjay Bhanot et al. · New England Journal of Medicine · 2014 · 622 citations · Full text

Medicine, Hematology, Molecular Genetics +11

Hematology: Basic Principles and Practice

LoAnn Peterson · American Journal of Clinical Pathology · 1995 · 520 citations

Life Sciences, Immunology, Pathobiology +17

RNA aptamers as reversible antagonists of coagulation factor IXa

Christopher P. Rusconi, Elizabeth Scardino, Juliana M. Layzer et al. · Nature · 2002 · 512 citations

Medicine, Molecular Biology, Molecular Medicine +13

A role for factor XIIa–mediated factor XI activation in thrombus formation in vivo

Qiufang Cheng, Erik I. Tucker, Meghann S. Pine et al. · Blood · 2010 · 262 citations · Full text

Medicine, Hematology, Molecular Biology +16

Polyphosphate is a cofactor for the activation of factor XI by thrombin

Sharon H. Choi, Stephanie A. Smith, James H. Morrissey · Blood · 2011 · 247 citations · Full text

Medicine, Biochemistry, Molecular Biology +12