Concepedia

Aptamer-based Targeting

Aptamer-Based Targeting is a molecular targeting strategy that utilizes single-stranded DNA or RNA oligonucleotides selected for high-affinity and specific binding to target biomolecules, enabling precise delivery of therapeutic or diagnostic agents in active targeting applications.

507

Publications

31.4K

Citations

2.9K

Authors

935

Institutions

Publications per year

2017–2026

273

Parents

Publications

507

Cell type–specific delivery of siRNAs with aptamer-siRNA chimeras

James O McNamara, Eran R. Andrechek, Yong Wang et al. · Nature Biotechnology · 2006 · 994 citations

, , +14

2′-Fluoropyrimidine RNA-based Aptamers to the 165-Amino Acid Form of Vascular Endothelial Growth Factor (VEGF165)

Judy Ruckman, Louis S. Green, Jim Beeson et al. · Journal of Biological Chemistry · 1998 · 735 citations · Full text

, , +14

An Aptamer–Doxorubicin Physical Conjugate as a Novel Targeted Drug‐Delivery Platform

Vaishali Bagalkot, Omid C. Farokhzad, Róbert Langer et al. · Angewandte Chemie International Edition · 2006 · 612 citations

, , +14

Systemic administration of optimized aptamer-siRNA chimeras promotes regression of PSMA-expressing tumors

Justin P. Dassie, Xiuying Liu, Gregory S. Thomas et al. · Nature Biotechnology · 2009 · 585 citations · Full text

, , +13

Oligonucleotide Aptamers: New Tools for Targeted Cancer Therapy

Hongguang Sun, Xun Zhu, Patrick Lu et al. · Molecular Therapy — Nucleic Acids · 2014 · 530 citations · Full text

, , +17

1–5 of 507

Authors

2.9K

  1. WT
    Weihong Tan

    Hunan University, China

    45 publications · 2.9K citations

    29

    h-index

  2. KA
    Khalil Abnous

    Mashhad University of Medical Sciences, Iran

    21 publications · 1.6K citations

    20

    h-index

  3. MR
    Mohammad Ramezani

    Mashhad University of Medical Sciences, Iran

    17 publications · 1.4K citations

    17

    h-index

  4. BA
    Bruce A. Sullenger

    Duke Medical Center, United States

    15 publications · 1.9K citations

    15

    h-index

  5. SM
    Seyed Mohammad Taghdisi

    Mashhad University of Medical Sciences, Iran

    14 publications · 841 citations

    14

    h-index

1–5 of 2.9K

Institutions

935

  1. Hunan University

    Changsha, China

    25 h-index

    203 publications

    10.8K citations

  2. Mashhad University of Medical Sciences

    Mashhad, Iran

    23 h-index

    138 publications

    9.2K citations

  3. Shanghai Jiao Tong University

    Shanghai, China

    21 h-index

    84 publications

    5.3K citations

  4. Renji Hospital

    Shanghai, China

    20 h-index

    75 publications

    4.4K citations

  5. Chinese Academy of Sciences

    Beijing, China

    19 h-index

    79 publications

    3.2K citations

  6. Interface (United States)

    La Grange, United States

    18 h-index

    113 publications

    7.5K citations

  7. University of Florida Health

    Gainesville, United States

    16 h-index

    83 publications

    6.2K citations

  8. University of Florida

    Gainesville, United States

    16 h-index

    99 publications

    4.1K citations

1–8 of 935

Venues

  1. Molecular Therapy — Nucleic Acids

    27 publications · 2.3K citations

    21

    h-index

  2. Biomaterials

    16 publications · 2.2K citations

    16

    h-index

  3. Angewandte Chemie International Edition

    16 publications · 2.2K citations

    15

    h-index

  4. Nucleic Acid Therapeutics

    13 publications · 586 citations

    13

    h-index

  5. Chemical Communications

    ChemComm · 13 publications · 797 citations

    12

    h-index

1–5