Claudette Bethune

Factor XI Antisense Oligonucleotide for Prevention of Venous Thrombosis

Harry R. Büller, Claudette Bethune, Sanjay Bhanot et al. · New England Journal of Medicine · 2014 · 622 citations · Full text

Medicine, Hematology, Molecular Genetics +11

Phase 2 Study of the Factor XI Antisense Inhibitor IONIS-FXIRx in Patients With ESRD

Michael Walsh, Claudette Bethune, Andrew Smyth et al. · Kidney International Reports · 2021 · 85 citations · Full text

Pharmacy, Pharmacology, Pharmacotherapy +17

Accumulation and elimination of dietary arsenobetaine in two species of fish, Atlantic salmon (<i>Salmo salar</i>L.) and Atlantic cod (<i>Gadus morhua</i>L.)

Heidi Amlund, Kevin A. Francesconi, Claudette Bethune et al. · Environmental Toxicology and Chemistry · 2006 · 60 citations

Veterinary Medicine, Pharmacokinetics, Toxicology +14

ISIS-FXIRx, A Novel and Specific Antisense Inhibitor of Factor XI, Caused Significant Reduction in FXI Antigen and Activity and Increased aPTT without Causing Bleeding in Healthy Volunteers

Que Liu, Claudette Bethune, Esmat Dessouki et al. · Blood · 2011 · 43 citations

Medicine, Hematology, Molecular Medicine +9

A Selective Inhibitor of Human C-reactive Protein Translation Is Efficacious In Vitro and in C-reactive Protein Transgenic Mice and Humans

Nicholas Jones, Melissa A. Pegues, Mark A. McCrory et al. · Molecular Therapy — Nucleic Acids · 2012 · 42 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +17