Concepedia

Publication | Open Access

Functional evidence for derivation of systemic histiocytic neoplasms from hematopoietic stem/progenitor cells

DOIFull Paper Access

128

Citations

18

References

2017

Year

Benjamin H. Durham, Damien Roos‐Weil, Claude Baillou, Fleur Cohen‐Aubart, Akihide Yoshimi, Makoto Miyara, Matthias Papo, Zofia Hélias‐Rodzewicz, Nathalie Terrones, Neval Özkaya,
Blood

Abstract

Key Points BRAF V600E mutations are detectable in hematopoietic stem and progenitors in adults with histiocytosis. Transplantation of CD34+ cells from histiocytosis patients can give rise to genetically and phenotypically accurate xenografts.

References

YearCitations

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