Concepedia

Histone Deacetylase Inhibitor SAHA Is a Promising Treatment of Cushing Disease

Jie Lu, Grégoire P. Chatain, Alejandro Bugarini, Xiang Wang, Dragan Maric, Stuart Walbridge, Zhengping Zhuang, Prashant Chittiboina

The Journal of Clinical Endocrinology & Metabolism · 2017 · 63 citations · 31 references

DOIFull text

Open access

Abstract

Our findings demonstrate SAHA's efficacy in reducing survival and ACTH secretion in AtT-20 and hCtT cells, providing a potential intervention for recurrent/unremitting CD.

References

31

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Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

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STRING v10: protein–protein interaction networks, integrated over the tree of life

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Bid, a Bcl2 Interacting Protein, Mediates Cytochrome c Release from Mitochondria in Response to Activation of Cell Surface Death Receptors

Xu Luo, I. Imawati Budihardjo, Hua Zou et al. · Cell · 1998 · 3.6K citations · Full text

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