PubMed · 2017 · 25 citations · 93 references
Open access
Life SciencesNeurobiologyNeuroscienceDementiaMolecular NeurobiologyMolecular NeuroscienceAmyloid FormationNeurodegeneration MechanismsNeurodegenerative DiseasesNeurodegenerative DisordersNeuroinflammationNeurotoxic MechanismsAlzheimer's Disease ModelsAmyloid Beta AggregationAmyloid Beta PeptidesAmyloid-beta-induced NeurotoxicityAnimal Disease ModelsAntibodiesSynaptic Plasticity DisruptionTau Hyperphosphorylation
Better understanding of the mechanism that makes attachment of AβOs to vulnerable neurons a neurotoxic phenomenon should open the door to therapeutics and diagnostics targeting the first step of a complex pathway that leads to neural damage and dementia.
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Amyloid Oligomers Exacerbate Tau Pathology in a Mouse Model of Tauopathy
Maj-Linda B. Selenica, Milene L. Brownlow, Jeffy P. Jimenez et al. · Neurodegenerative Diseases · 2012 · 10.4K citations · Full text
Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade
Clifford R. Jack, David S. Knopman, William J. Jagust et al. · The Lancet Neurology · 2009 · 4.8K citations · Full text