Designer Probiotics: Paving the Way to Living Therapeutics

A Phase I Trial With Transgenic Bacteria Expressing Interleukin-10 in Crohn’s Disease

Henri Braat, Pieter Rottiers, Daniël W. Hommes et al. · Clinical Gastroenterology and Hepatology · 2006 · 770 citations

Life Sciences, Immunology, Microbiology +14

Programmable probiotics for detection of cancer in urine

Tal Danino, Arthur Prindle, Gabriel A. Kwong et al. · Science Translational Medicine · 2015 · 462 citations · Full text

Life Sciences, Biotechnology, Cancer Biology +14

Incorporation of therapeutically modified bacteria into gut microbiota inhibits obesity

Zhongyi Chen, Lilu Guo, Yongqin Zhang et al. · Journal of Clinical Investigation · 2014 · 277 citations · Full text

Life Sciences, Microbiology, Nutritional Sciences +16

Prevention of vaginal SHIV transmission in macaques by a live recombinant Lactobacillus

L A Lagenaur, Brigitte E. Sanders-Beer, Beda Břicháček et al. · Mucosal Immunology · 2011 · 173 citations · Full text

Life Sciences, Infectious Diseases, Microbiology +17

Development of a Stress-Inducible Controlled Expression (SICE) system in Lactococcus lactis for the production and delivery of therapeutic molecules at mucosal surfaces

Bouasria Benbouziane, Pedro Ribelles, Camille Aubry et al. · Journal of Biotechnology · 2013 · 111 citations

Life Sciences, Biotechnology, Microbiology +15