Journal of the Pediatric Infectious Diseases Society · 2017 · 55 citations · 15 references
Veterinary MedicineInfectious DiseasesPediatricsImmunizationVaccinologyVirologyAdult ImmunizationClinical Vaccine TrialsPediatric ImmunizationVaccinationVaccine DevelopmentViral VaccinesHuman Metapneumovirus InfectionPediatric VaccinationPediatric Vaccine DevelopmentPediatric Vaccine EfficacyPediatric Vaccine TrialsPediatric Viral InfectionsRoutine Childhood VaccinationVaccination Responses In Children
We conducted a phase I clinical trial of an experimental live attenuated recombinant human metapneumovirus (HMPV) vaccine (rHMPV-Pa) sequentially in adults, HMPV-seropositive children, and HMPV-seronegative children, the target population for vaccination. rHMPV-Pa was appropriately restricted in replication in adults and HMPV-seropositive children but was overattenuated for HMPV-seronegative children.
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Community-Acquired Pneumonia Requiring Hospitalization among U.S. Children
Seema Jain, Derek J. Williams, Sandra R. Arnold et al. · New England Journal of Medicine · 2015 · 1.8K citations · Full text