Ionizing radiation induces long-term senescence in endothelial cells through mitochondrial respiratory complex II dysfunction and superoxide generation

A biomarker that identifies senescent human cells in culture and in aging skin in vivo.

Goberdhan P. Dimri, X Lee, George Basile et al. · Proceedings of the National Academy of Sciences · 1995 · 7.4K citations · Full text

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Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor

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Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion

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Enhanced Phosphorylation of p53 by ATM in Response to DNA Damage

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A Chemical Inhibitor of p53 That Protects Mice from the Side Effects of Cancer Therapy

Pavel G. Komarov, Elena A. Komarova, Roman V. Kondratov et al. · Science · 1999 · 1.3K citations

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