Concepedia

Discovery and optimization of selective RET inhibitors via scaffold hopping

Zhibo Luo, Lingli Wang, Zhifei Fu, Bin Shuai, Miaorong Luo, Guoping Hu, Jian Chen, Jikui Sun, Jiansong Wang, Jian Li,

Bioorganic & Medicinal Chemistry Letters · 2021 · 25 citations · 41 references

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41

Sorafenib in Advanced Hepatocellular Carcinoma

Josep M. Llovet, Sergio Ricci, Vincenzo Mazzaferro et al. · New England Journal of Medicine · 2008 · 13K citations · Full text

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Vandetanib in Patients With Locally Advanced or Metastatic Medullary Thyroid Cancer: A Randomized, Double-Blind Phase III Trial

Samuel A. Wells, Bruce G. Robinson, Robert F. Gagel et al. · Journal of Clinical Oncology · 2011 · 1.6K citations · Full text

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High prevalence of BRAF mutations in thyroid cancer: genetic evidence for constitutive activation of the RET/PTC-RAS-BRAF signaling pathway in papillary thyroid carcinoma.

Edna Teruko Kimura, Marina N. Nikiforova, Zhaowen Zhu et al. · PubMed · 2003 · 1.5K citations

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Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma

Cécile Guichard, Giuliana Amaddeo, Sandrine Imbeaud et al. · Nature Genetics · 2012 · 1.4K citations · Full text

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Mutations in the RET proto-oncogene are associated with MEN 2A and FMTC

Helen Donis-Keller, Shenshen Dou, David Chi et al. · Human Molecular Genetics · 1993 · 1.3K citations

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