Concepedia

Identification of selective inhibitors of sphingosine kinases 1 and 2 through a structure–activity relationship study of 4-epi-jaspine B

Hiroaki Ohno, Maho Honda, Naoka Hamada, Jun Miyagaki, Akira Iwata, Kazuhiro Otsuki, Toru Maruyama, Shinya Nakamura, Isao Nakanishi, Shinsuke Inuki,

Bioorganic & Medicinal Chemistry · 2017 · 13 citations · 39 references

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References

39

Regulation of Histone Acetylation in the Nucleus by Sphingosine-1-Phosphate

Nitai C. Hait, Jeremy C. Allegood, Michael Maceyka et al. · Science · 2009 · 977 citations · Full text

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Discovery and evaluation of inhibitors of human sphingosine kinase.

Kevin J. French, Randy S. Schrecengost, Brian D. Lee et al. · PubMed · 2003 · 600 citations

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Sphingosine Kinase 2 Is a Nuclear Protein and Inhibits DNA Synthesis

Nobuaki Igarashi, Taro Okada, Shun Hayashi et al. · Journal of Biological Chemistry · 2003 · 411 citations · Full text

, , +15

Sphingosine Kinase-1 Expression Correlates With Poor Survival of Patients With Glioblastoma Multiforme: Roles of Sphingosine Kinase Isoforms in Growth of Glioblastoma Cell Lines

James R. Van Brocklyn, Catherine A. Jackson, Dennis K. Pearl et al. · Journal of Neuropathology & Experimental Neurology · 2005 · 327 citations · Full text

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Pharmacology and Antitumor Activity of ABC294640, a Selective Inhibitor of Sphingosine Kinase-2

Kevin J. French, Yan Zhuang, Lynn W. Maines et al. · Journal of Pharmacology and Experimental Therapeutics · 2010 · 315 citations · Full text

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