Concepedia

Long Noncoding RNA PVT1 Promotes EMT and Cell Proliferation and Migration Through Downregulating p21 in Pancreatic Cancer Cells

Baoqiang Wu, Yong Jiang, Feng Zhu, Donglin Sun, Xiaozhou He

Technology in Cancer Research & Treatment · 2017 · 71 citations · 20 references

DOIFull text

Open access

Abstract

Plasmacytoma variant translocation 1 promoted epithelial-mesenchymal transition and cell proliferation and migration through downregulating p21 in pancreatic cancer cells.

References

20

Cancer statistics, 2015

Rebecca L. Siegel, Kimberly D. Miller, Ahmedin Jemal · CA A Cancer Journal for Clinicians · 2015 · 11.9K citations · Full text

Oncofetal long noncoding RNA PVT1 promotes proliferation and stem cell-like property of hepatocellular carcinoma cells by stabilizing NOP2

Fang Wang, Ji‐hang Yuan, Shao-Bing Wang et al. · Hepatology · 2014 · 455 citations · Full text

Amplification of <i>PVT1</i> Contributes to the Pathophysiology of Ovarian and Breast Cancer

Yinghui Guan, Wen-Lin Kuo, Jackie L. Stilwell et al. · Clinical Cancer Research · 2007 · 346 citations · Full text

Long noncoding RNA PVT1 indicates a poor prognosis of gastric cancer and promotes cell proliferation through epigenetically regulating p15 and p16

Rong Kong, Erbao Zhang, Dandan Yin et al. · Molecular Cancer · 2015 · 311 citations · Full text

Amplification of PVT-1 is involved in poor prognosis via apoptosis inhibition in colorectal cancers

Yusuke Takahashi, Genta Sawada, Jyunji Kurashige et al. · British Journal of Cancer · 2013 · 287 citations · Full text

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