Biotransformation of 2,4-toluenediamine in human skin and reconstructed tissues

Comparison of human skin or epidermis models with human and animal skin in in-vitro percutaneous absorption

Fritz P. Schmook, Josef G. Meingassner, Andreas Billich · International Journal of Pharmaceutics · 2001 · 525 citations

Pharmacy, Dermatology, Pharmacokinetics +16

Metabolic activation and deactivation of arylamine carcinogens by recombinant human NAT1 and polymorphic NAT2 acetyltransferases

David W. Hein, Mark A. Doll, Timothy D. Rustan et al. · Carcinogenesis · 1993 · 356 citations

Medicine, Pharmacology, Toxicology +16

The Use of Reconstructed Human Epidermis for Skin Absorption Testing: Results of the Validation Study

Monika Schäfer‐Korting, Udo Bock, W. Diembeck et al. · Alternatives to Laboratory Animals · 2008 · 230 citations

Pharmacy, Dermatology, Bioavailability +14

Recommended lists of genotoxic and non-genotoxic chemicals for assessment of the performance of new or improved genotoxicity tests: A follow-up to an ECVAM workshop

David Kirkland, Peter Kasper, Lutz Müller et al. · Mutation Research/Genetic Toxicology and Environmental Mutagenesis · 2008 · 172 citations

Pharmacy, Toxicology, Environmental Toxicology +12

Langerhans Cells Facilitate Epithelial DNA Damage and Squamous Cell Carcinoma

Badri Modi, Jason H. Neustadter, Elisa Binda et al. · Science · 2012 · 145 citations · Full text

Medicine, Immunology, Oncology +12