Timothy D. Rustan

Metabolic activation and deactivation of arylamine carcinogens by recombinant human NAT1 and polymorphic NAT2 acetyltransferases

David W. Hein, Mark A. Doll, Timothy D. Rustan et al. · Carcinogenesis · 1993 · 355 citations

Metabolic activation of N-hydroxyarylamines and N-hydroxyarylamides by 16 recombinant human NAT2 allozymes: effects of 7 specific NAT2 nucleic acid substitutions.

David W. Hein, Mark A. Doll, Timothy D. Rustan et al. · PubMed · 1995 · 129 citations

Chemical Biology, Polymorphic Nat2 Alleles, Nucleic Acid Chemistry +15

Molecular genetics of human polymorphic N-acetyltransferase: enzymatic analysis of 15 recombinant wild-type, mutant, and chimeric NAT2 allozymes

David W. Heln, Ronald J. Ferguson, Mark A. Doll et al. · Human Molecular Genetics · 1994 · 120 citations

Allelic Variant, Human Polymorphic N-acetyltransferase, Genetics +14

Metabolic activation of aromatic and heterocyclicN-hydroxyarylamines by wild-type and mutant recombinant human NAT1 and NAT2 acetyltransferases

David W. Hein, Timothy D. Rustan, Ronald J. Ferguson et al. · Archives of Toxicology · 1994 · 109 citations

Nat2 Acetyltransferases, Biochemistry, Metabolic Activation +8

Human N-acetylation of benzidine: role of NAT1 and NAT2.

Terry V. Zenser, Vijaya M. Lakshmi, Timothy D. Rustan et al. · PubMed · 1996 · 83 citations

Human Liver Slices, Human N-acetylation, Nitrosative Stress +19