Concepedia

MicroRNA-448 promotes multiple sclerosis development through induction of Th17 response through targeting protein tyrosine phosphatase non-receptor type 2 (PTPN2)

Rihan Wu, Qinyu He, Haitao Chen, Miao Xu, Ning Zhao, Ying Xiao, Qianqian Tu, Wenjun Zhang, Xiaoying Bi

Biochemical and Biophysical Research Communications · 2017 · 43 citations · 20 references

DOI

Concepts

References

20

IL-23 drives a pathogenic T cell population that induces autoimmune inflammation

Claire L. Langrish, Yi Chen, Wendy M. Blumenschein et al. · The Journal of Experimental Medicine · 2005 · 4K citations · Full text

, , +17

Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain

Jonathan Sherlock, Yi Chen, Craig A. Murphy et al. · Nature · 2003 · 2.9K citations

, , +14

Monoclonal Anti–Interleukin 23 Reverses Active Colitis in a T Cell–Mediated Model in Mice

Charles O. Elson, Yingzi Cong, Casey T. Weaver et al. · Gastroenterology · 2007 · 447 citations

, , +16

Serum neurofilament light chain in early relapsing remitting MS is increased and correlates with CSF levels and with MRI measures of disease severity

Jens Kühle, Christian Barro, Giulio Disanto et al. · Multiple Sclerosis Journal · 2016 · 250 citations

, , +17

MicroRNA-21 promotes Th17 differentiation and mediates experimental autoimmune encephalomyelitis

Gopal Murugaiyan, Andre Pires da Cunha, Amrendra K. Ajay et al. · Journal of Clinical Investigation · 2015 · 239 citations · Full text

, , +17