Concepedia

THEMIS enhances TCR signaling and enables positive selection by selective inhibition of the phosphatase SHP-1

Seeyoung Choi, Claude C. Warzecha, Ekaterina Zvezdova, Jan Lee, Jérémy Argenty, Renaud Lesourne, L. Aravind, Paul E. Love

Nature Immunology · 2017 · 82 citations · 33 references

DOIFull text

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Concepts

References

33

A Critical Role for Dnmt1 and DNA Methylation in T Cell Development, Function, and Survival

Peggy P. Lee, David Fitzpatrick, Caroline Beard et al. · Immunity · 2001 · 1.3K citations · Full text

, , +16

Mechanism of Inhibition of Protein-tyrosine Phosphatases by Vanadate and Pervanadate

Gregory Huyer, Susana Liu, John A. Kelly et al. · Journal of Biological Chemistry · 1997 · 827 citations · Full text

, , +15

TCR ligand discrimination is enforced by competing ERK positive and SHP-1 negative feedback pathways

Irena Štefanová, Bernhard Hemmer, Marco Vergelli et al. · Nature Immunology · 2003 · 464 citations

, , +14

Discrete Generation of Superoxide and Hydrogen Peroxide by T Cell Receptor Stimulation

Satish Devadas, Luba Zaritskaya, Sue Goo Rhee et al. · The Journal of Experimental Medicine · 2002 · 458 citations · Full text

, , +17

T cells express a phagocyte-type NADPH oxidase that is activated after T cell receptor stimulation

Sharon H. Jackson, Satish Devadas, Jaeyul Kwon et al. · Nature Immunology · 2004 · 450 citations

, , +15