Concepedia

TCR ligand discrimination is enforced by competing ERK positive and SHP-1 negative feedback pathways

Irena Štefanová, Bernhard Hemmer, Marco Vergelli, Roland Martinꝉ, William E. Biddison, Ronald N. Germain

Nature Immunology · 2003 · 464 citations · 58 references

DOI

Concepts

References

58

SH2 domains recognize specific phosphopeptide sequences

Cell · 1993 · 2.7K citations

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RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

Yoichi Shinkai · Cell · 1992 · 2.6K citations

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The Biochemical Basis of an All-or-None Cell Fate Switch in <i>Xenopus</i> Oocytes

James E. Ferrell, Eric M. Machleder · Science · 1998 · 1.1K citations

, , +17

The presence of interleukin 4 during in vitro priming determines the lymphokine-producing potential of CD4+ T cells from T cell receptor transgenic mice.

Robert A. Seder, W E Paul, Mark M. Davis et al. · The Journal of Experimental Medicine · 1992 · 1K citations · Full text

, , +17

Kinetic proofreading in T-cell receptor signal transduction.

Timothy W. McKeithan · Proceedings of the National Academy of Sciences · 1995 · 985 citations

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